[malboroman]

There are some basic apps you would surely need to be familiar with:

1: Graphics app (Like photoshop and paint shop pro(BAH!!!))
2: Vector app (Like illustrator, Flash and Freehand)
3: 3D app (3D studio max, Maya, Cinema 4D and off course Realsoft(5-0 wouldn't forgive me if I left this out))

All by all it is good to know a bit of everything, but it is essential that specialize in a few aspects of the wide variaty of programs there are available...