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I always work with 300 DPI. Once I have finished whatever I happen to be working on at the time I save both PSD and JPEG versions of my art. (And as a png when applicable) I have printed of countless copies of my art with no problem whatsoever. If you are emailing a "rough" copy use the "save for web" option. Otherwise save it as the full sized jpeg/tiff file and upload to somewhere like 4 shared and send the link in an email so the recipient can DL the larger file themselves.
As long as your original was created at around 300 dpi and you save at the highest quality you can you should not have a problem.... other than file size that is lol
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